Correlation of STN-DBS Induced Visuospatial Changes and Freezing of Gait

Launched by MEDICAL UNIVERSITY OF SOUTH CAROLINA · May 20, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how a treatment called deep brain stimulation (DBS) impacts attention and visual skills in people with Parkinson's disease, particularly those who experience freezing of gait (FOG). FOG is when a person suddenly feels like their feet are glued to the ground, making it difficult to walk. The study aims to understand how problems with visual attention might relate to FOG, especially since some research suggests that stimulating the right side of the brain may help improve this issue.

To participate in the trial, individuals need to be over 18 years old and have undergone bilateral STN-DBS surgery for their Parkinson's disease. However, people with uncorrected vision or hearing problems, those who are pregnant, or individuals with dementia or brain issues that affect thinking or movement cannot take part. If eligible, participants can expect to contribute to important research that may help improve treatments for FOG, as well as gain insights into their own condition. The study is currently recruiting participants of all genders, ages 65 to 74.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Subjects above 18 years of age
• • Subjects with freezing of gait
• • Subjects with bilateral STN-DBS surgery as part of their clinical care for Parkinson's disease
• Exclusion Criteria:
• • Uncorrected visual or hearing impairments, as indicated by self-report
• • Individuals who are pregnant or expect to become pregnant during the course of the study
• • Individuals with dementia or relevant brain lesions impacting cognition or gait