Discontinuation of Tobacco Dependence in Smoking Patients With Squamous Cell Carcinoma of the Head-neck District: Multicenter Prospective Observational Study

Launched by AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI · May 26, 2025

Keywords

ClinConnect Summary

This clinical trial is looking to help patients with squamous cell carcinoma of the head and neck (a type of cancer that affects areas like the mouth and throat) quit smoking after they receive their diagnosis. The main goal is to see how effective a specific counseling program is in encouraging these patients to stop smoking for at least six months. The success of the program will be measured by the number of patients who manage to quit smoking altogether during this time.

To participate in this study, individuals need to be at least 18 years old and actively smoking or have quit smoking for less than 30 days when they are diagnosed with this type of cancer. The trial is open to patients who are planning to undergo treatments like surgery or radiation aimed at curing their cancer. It's important to note that those who have already quit smoking for more than 30 days or are only using e-cigarettes are not eligible. While the trial is not yet recruiting participants, those who do take part can expect to receive supportive counseling aimed at helping them stop smoking, which can improve their overall health and treatment outcomes.

Gender

ALL

Eligibility criteria

• • Inclusion criteria.
• • Patients with SCCHN tumors of the oral cavity, oropharynx, hypopharynx, larynx, nasopharynx, and paranasal sinuses.
• • Patients older than 18 years of age with SCCHN of these sites who are candidates for surgical/radiotherapy (RT)/radiochemotherapy (RTCT) treatment with curative intent (primary treatment).
• • Patients with SCCHN who are active smokers, or have quit smoking for less than 30 days, at the time of initiation of the process (visits and instrumental tests) that led to the diagnosis of cancer
• • Exclusion criteria
• • Patients with SCCHN cancer who have quit smoking for more than 30 days at the time of initiation of the diagnostic process.
• • Patients using only e-cigarettes at the time of initiation of the treatment process.
• • Patients with non-SCCHN cancer in recurrent metastatic stage and not eligible for curative purpose therapy.