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Search / Trial NCT06995586

Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.

Launched by NICOSIA GENERAL HOSPITAL · May 21, 2025

Trial Information

Current as of July 23, 2025

Not yet recruiting

Keywords

Cardio Pulmonary Bypass Cardiovascular Diseases Omega 3 Polyunsaturated Fatty Acids Vitamin C Antioxidants Lactulose Omega 3 Supplementation Supplements Postoperative Optimal Medical Therapy Cabg Coronary Artery Bypass Grafting Postoperative Depression Lignin Adsorbent Prebiotics

ClinConnect Summary

This clinical trial is studying the effects of certain dietary supplements on patients who have undergone coronary artery bypass grafting (CABG), a surgery that helps improve blood flow to the heart. The trial aims to see if adding Vitamin C, Omega-3 fatty acids (found in fish oil), lignin (a type of dietary fiber), and lactulose (a substance that supports gut health) to the usual medications after surgery can help improve patients' recovery and overall well-being.

To participate in this trial, you need to be between 40 and 80 years old, have coronary artery disease, and be mentally clear, meaning you can understand what the study involves. If you qualify and choose to join, you will be randomly assigned to either receive the supplements along with your regular medications or to just take your usual medications. The study will track your health and recovery over about six months to see how the supplements may help. It’s important to note that participants cannot have certain medical conditions or be taking specific medications that could interfere with the study.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • The subjects will be people 40-80 years old, with coronary artery disease, and mental clarity who will undergo Coronary Aortic Bypass (CABG) in our clinic (Public Cardiothoracic Surgery clinic in Nicosia General Hospital) and will be randomized into 2 groups (intervention group and control group).
  • Signed consent form
  • Ability to adhere to the protocol
  • Exclusion Criteria:
  • Any psychiatric, neurological or motor disorder.
  • Hypersensitivity to the components of the supplement.
  • Combined Cardiac Surgery other than CABG and valve or aortic
  • Concurrent participation in other clinical trials.
  • Previous use of any probiotics, prebiotics, adsorbent dietary supplements, Vitamin C and/or Omega 3 fatty acids.

About Nicosia General Hospital

Nicosia General Hospital is a leading healthcare institution in Cyprus, dedicated to advancing medical research and improving patient outcomes. As a clinical trial sponsor, the hospital is committed to conducting high-quality, ethically sound research that adheres to international standards. With a team of experienced researchers and healthcare professionals, Nicosia General Hospital focuses on a wide range of therapeutic areas, aiming to contribute valuable insights to the medical community. The institution prioritizes patient safety and welfare throughout the trial process, ensuring transparency and adherence to regulatory guidelines. Through its clinical trials, Nicosia General Hospital strives to innovate and enhance treatment options for various health conditions, ultimately benefiting patients both locally and globally.

Locations

Strovolos, Nicosia, Cyprus

Patients applied

0 patients applied

Trial Officials

Elpidoforos S. Soteriades, MD, Ass Prof

Study Chair

Open University of Cyprus

Athanasios D. Athanasiou, MD, MSc, MPA

Principal Investigator

Nicosia General Hospital

Elpidoforos S. Soteriades, MD, Ass Prof

Study Director

Open University of Cyprus

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported