Improving Diagnosis of Legume Allergy in Children

Launched by CENTRAL HOSPITAL, NANCY, FRANCE · May 21, 2025

Keywords

ClinConnect Summary

This clinical trial, called the LACID study, is focused on improving the way we diagnose legume allergies in children. Legumes, which include peanuts, soy, lentils, peas, lupin, chickpeas, beans, and fenugreek, can cause serious allergic reactions, but only a few of these foods are required to be clearly labeled on packaging in Europe. This makes it challenging for families to identify hidden allergens in processed foods, especially as more schools are serving vegetarian meals that often contain legumes. The study aims to find and analyze the proteins in lupin, fenugreek, and peas that might cause allergies, with the goal of developing better allergy tests.

To participate in the trial, children must be sensitized to lupin, fenugreek, or pea, which means their bodies have shown a reaction to these foods, even if they haven't had a real allergic reaction. However, children currently undergoing certain treatments are not eligible. Participants will undergo tests that may help identify which legumes they truly need to avoid, making everyday life easier and less stressful for families. This research could lead to quicker and more accurate diagnoses, allowing children to enjoy more foods safely.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Sensitised to lupine, fenugreek or pea
• Exclusion Criteria:
• • on going anti-IgE treatment or in the last 6 months