Promotion of Vaginal Health With CH2 Vaginal Gel After Pelvic Radiotherapy

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · May 21, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of using CH2 vaginal gel to improve vaginal health in women who have completed pelvic radiotherapy for gynecologic cancer. The study aims to see how well this gel works compared to vaginal rehabilitation exercises over a 12-week period. Researchers will measure the changes in sexual function using a specific scoring system designed for women.

To be eligible for the trial, participants need to be female, between the ages of 20 and 70, and must have finished their pelvic radiotherapy treatment. Women who have serious health issues that could affect their participation, or those currently undergoing treatment for cancer, are not eligible. If you choose to participate, you’ll either receive the CH2 gel or be guided through exercises to help improve your vaginal health, and your progress will be monitored throughout the study. This trial is actively recruiting participants, so it's a great opportunity to contribute to research that may help improve the quality of life for women in similar situations.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Female patients aged between 20 and 70 years.
• • 2. Completion of pelvic radiotherapy for gynecologic cancer, which may include external beam radiotherapy (EBRT), brachytherapy (BT), or a combination of both.
• • 3. Eastern Cooperative Oncology Group (ECOG) performance status score of 0-1.
• Exclusion Criteria:
• • 1. Individuals under the age of 18.
• • 2. Presence of distant metastases or a history of malignancy currently under treatment within the past five years (excluding non-melanoma skin cancer).
• • 3. Presence of severe comorbidities, such as uncontrolled diabetes, cardiovascular disease, or autoimmune disorders that may interfere with treatment or study participation.
• • 4. Diagnosed psychiatric disorders or significant social factors that may prevent adherence to study requirements or completion of follow-up evaluations.
• • 5. Inability to self-administer vaginal gel or vaginal rehabilitation exercises.