Minimally Invasive Protocols for the Treatment and Control of Caries Lesions in Children and Adolescents

Launched by UNIVERSITY OF NOVE DE JULHO · May 21, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at new ways to prevent and treat dental cavities, also known as caries, in children and adolescents aged 6 to 12 years. The study will involve about 50,000 children from five cities in Brazil who will receive dental check-ups and preventive treatments to help keep their teeth healthy. For those diagnosed with cavities, around 2,500 children will receive specific treatments based on how severe their cavities are. All participants will have follow-up visits every three months for two years to monitor their progress.

To be eligible for this study, children must be between 6 and 12 years old, have at least one permanent molar tooth, and have active cavities that need treatment. Parents or guardians will need to provide written consent, and children will need to agree to participate as well. It’s important to note that children with certain medical conditions or those who are already involved in other dental studies may not be able to participate. This trial aims to improve dental care for children, making it less invasive and more effective in preventing cavities.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children aged between 6 and 12 years at the time of enrollment
• • Presence of at least one erupted permanent first molar
• • Diagnosis of active caries lesions classified according to ICDAS (scores 1 to 6)
• • Written informed consent signed by a legal guardian and assent signed by the child
• • Ability to attend quarterly follow-up visits over a 24-month period
• Exclusion Criteria:
• • Children requiring endodontic treatment or presenting extensive pulpal involvement
• • Presence of systemic diseases or medical conditions that contraindicate dental care
• • Known allergy to any material used in the study (fluoride varnish, high-viscosity glass ionomer cement)
• • Participation in other clinical dental studies that could interfere with the outcomes