Prospective Randomized Observer Blinded Single Center Study Comparing 90-day Functional Outcome in Patients Who Received Intravenous Propofol Infusion Versus Inhalational Sevoflurane for General Anesthesia During Mechanical Thrombectomy in Patients Who Suffered From Acute Ischemic Stroke

Launched by UNIVERSITY OF KANSAS MEDICAL CENTER · May 23, 2025

Keywords

ClinConnect Summary

This clinical trial is looking to understand which method of anesthesia is better for patients undergoing a specific type of surgery called mechanical thrombectomy, which is used to treat acute ischemic stroke. The study will compare two ways to give anesthesia: one through inhaling a gas called sevoflurane and the other through an intravenous (IV) infusion of a medication called propofol. By studying the outcomes of patients who receive these different types of anesthesia, doctors hope to find out which method results in better recovery after surgery.

To participate in this trial, you need to be over 18 years old and have had an acute ischemic stroke that requires this specific treatment. Unfortunately, people under 18, pregnant women, and those with certain medical conditions or allergies will not be eligible. If you join the study, you will receive either form of anesthesia during your surgery, and researchers will follow your recovery over the next 90 days to see how well you do. This information will help doctors make informed choices about anesthesia options for stroke patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • \>18 years Acute ischemic stroke requiring endovascular treatment.
• Exclusion Criteria:
• • \<18 years
• • Pregnant patients
• • Patients with malignant hyperthermia
• • Allergies or any contraindications to either inhalational or intravenous agents
• • Patients already on intravenous anesthetic infusions
• • Prisoners
• • Students and employees