Erector Spinae Block Vs Ketamine-based Multimodal Analgesia Protocol in Lumber Decompressive Surgery
Launched by KASR EL AINI HOSPITAL · Jun 2, 2025
Trial Information
Current as of June 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at two different methods to help manage pain after spine surgery, specifically lumbar decompression surgery. The study will compare the effectiveness of a technique called the erector spinae plane block (ESPB) with a pain relief approach that includes ketamine and other medications. The goal is to see which method helps patients recover better after their surgery.
To be eligible for this trial, participants should be between the ages of 18 and older and scheduled for open lumbar decompression surgery for conditions like spinal stenosis or trauma affecting one or two levels of the spine. Some people may not qualify if they have certain health problems, a history of opioid abuse, or allergies to the study medications. If someone joins the study, they will receive either the ESPB or the ketamine-based treatment and will be monitored for their recovery and pain levels to help determine which option is more effective.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • American Society of Anesthesiologists (ASA) status of I-III
- • scheduled for open lumber decompression surgery for degenerative stenosis or trauma involving 1or 2 levels without fusion.
- Exclusion Criteria:
- • Refusal to participate
- • Contraindication for peripheral regional anesthesia such as infection and coagulopathy.
- • Inability to comprehend the Numeric Rating Scale (NRS) or Patients who has cognitive function impairment
- • Preoperative renal or hepatic insufficiency
- • History of Opioid abuse.
- • Allergy to any of the study drugs
About Kasr El Aini Hospital
Kasr El Aini Hospital, a prestigious medical institution affiliated with Cairo University, is dedicated to advancing healthcare through innovative clinical research. With a commitment to excellence, the hospital serves as a leading sponsor of clinical trials, leveraging its state-of-the-art facilities and a multidisciplinary team of healthcare professionals. The institution focuses on a diverse range of therapeutic areas, aiming to improve patient outcomes and contribute to the global medical community. By fostering collaboration and adhering to the highest ethical standards, Kasr El Aini Hospital plays a pivotal role in the development of new treatments and therapies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported