Ventilator Inspiratory Trigger Sensitivity Adjustment Versus Threshold Device Training on Pulmonary Functions in Acute Stroke Patients

Launched by AL-ZAYTOONAH UNIVERSITY OF JORDAN · Jun 2, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at two different methods to help improve breathing in patients who have had a stroke and are on mechanical ventilation (a machine that helps them breathe). The study aims to understand whether adjusting the sensitivity of the ventilator’s trigger or training with a special device is more effective in strengthening the respiratory muscles of these patients. This is important because many stroke patients experience weakness in their breathing muscles, which can make it harder for them to come off the ventilator and recover fully.

To be eligible for the trial, participants must be adults aged 40 to 60 years who have been diagnosed with an acute stroke. They should have a certain level of consciousness and stable oxygen levels. However, individuals with serious heart problems, severe breathing difficulties, or certain muscle and spinal conditions will not be able to participate. If someone joins the study, they can expect to receive either method of training and be monitored closely to see how their breathing improves. This research could lead to better ways of helping stroke patients regain their ability to breathe on their own.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults aged 40-60 years.
• • Diagnosed with acute stroke patients.
• • Body mass index (BMI) 18:35 kg/m².
• • conscious oriented patients with Glasgow coma score ≥ 13.
• • PH\>7.25 and arterial oxygen saturation \>90%
• Exclusion Criteria:
• • Persistent hemodynamic instability as life threatening arrhythmias, acute heart failure, angina.
• • Severe breathlessness when spontaneously breathing.
• • Any progressive neuromuscular disease that would interfere with responding to inspiratory muscle training.
• • Spinal cord injuries.
• • Skeletal pathology (scoliosis, flail chest, spinal instrumentation) that would seriously impair the movement of the chest wall and ribs.
• • Patients on heavy sedation and respiratory muscle paralysis