Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy

Launched by UPPSALA UNIVERSITY · May 26, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at a treatment called Negative Pressure Wound Therapy (NPWT) for adults who have had emergency surgery called a laparotomy, which involves making a large cut in the abdomen. The main goal is to find out if using NPWT can help reduce problems with healing, like infections or wounds opening up again, compared to regular bandages.

To be eligible for this trial, participants need to be 18 years or older and have a surgical incision that is more than 10 cm long from their emergency laparotomy. They must also be able to give their consent to join the study. Unfortunately, people who have certain conditions, like severe cognitive impairment, or those who are pregnant or breastfeeding, cannot participate. If you join this trial, you’ll receive either the NPWT or standard dressing to see which works better for healing. It's important to know that this study is not yet recruiting participants, so it will start at a later date.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ≥18 years old
• • Written informed consent
• • \>10 cm midline incision with primary skin closure
• • Emergency laparotomy
• Exclusion Criteria:
• • Not able to consent (e.g. dementia, impaired cognitive function, unconscious)
• • Subjects not possible to follow up as assessed by the Investigator
• • Allergy to dressing material
• • Pregnancy or breastfeeding (females of childbearing potential)
• • Previous enrolment in the current study
• • Expected reoperation with 28 days of index laparotomy
• • Emergency laparotomy within 3 months