Proving Utility of a New Field-cycling MRI Prototype in Acute Stroke Patients

Launched by UNIVERSITY OF ABERDEEN · May 26, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new type of MRI scanner called Field-Cycling Imaging (FCI) to see if it can help doctors better understand brain changes in patients who have had a stroke. The main goal is to find out if this new scanning method can identify areas of the brain that might recover quickly after a stroke caused by a blocked blood vessel or bleeding. Participants in the study will have both a standard MRI and the new FCI scan soon after they arrive at the hospital, allowing researchers to gather important information about their condition.

To be eligible for the trial, participants must be experiencing an acute stroke (which means it started less than 24 hours ago) and have certain severity levels of stroke symptoms. They should also be able to undergo both types of MRI scans within this time frame. If someone joins the study, they can expect to have their scans done shortly after they arrive at the hospital, and those who had a blockage will return for follow-up visits 30 days later for additional scans and blood samples. It's important to note that this study is not yet recruiting participants, so it’s a good idea to keep an eye out for when it begins.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Acute stroke (\<24 hours from symptom onset).
• • NIHSS ≥4 and \<25 with cortical involvement and/or large vessel occlusion on baseline imaging.
• • Able to undergo 3T and FCI MRI \<24h of onset.
• • With or without thrombolysis.
• Exclusion Criteria:
• • Contraindications to MRI.
• • Medically unstable.
• • Unable to comprehend or comply with instructions regarding scanning
• • Prior mRS of \>3.
• • Identified for thrombectomy.
• • Non-stroke pathology or previous cortical infarct on CT scan \> 1/3 of middle cerebral artery territory.