Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）

Launched by RUIJIN HOSPITAL · May 26, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at different ways to manage drainage after a specific type of surgery for esophageal cancer called minimally invasive esophagectomy. The researchers want to compare three methods of drainage to see which one leads to less pain and fewer complications after surgery. By understanding which method works best, they hope to improve recovery for patients undergoing this procedure.

To participate in the trial, you need to be at least 18 years old and have a confirmed diagnosis of esophageal cancer that requires surgery involving three incisions: one in the neck, one in the chest, and one in the abdomen. You should be in good overall health (classes I-III on the ASA scale) and not have a history of chronic pain or serious heart and lung issues. If you join, you can expect close monitoring during your surgery and recovery, and you’ll help provide important information that could benefit future patients. The trial is currently looking for participants, so if this sounds like you or someone you know, it could be a great opportunity to contribute to medical research.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18 years
• • Pathologically confirmed esophageal cancer requiring three-incision esophagectomy (cervical, thoracic, and abdominal incisions)
• • ASA physical status class I-III
• Exclusion Criteria:
• • History of chronic pain or long-term use of analgesics prior to surgery
• • Severe cardiopulmonary dysfunction (e.g., FEV1 \<50%)
• • Coagulation disorders or patients undergoing reoperation
• • Intraoperative findings of extensive pleural adhesions, combined resection of adjacent organs, or other conditions deemed by the investigator to warrant exclusion