PARAtracheal vs CRIcoid Pressure on GLIttic DEformation (PARAGLIDE)

Launched by UNIVERSITY OF LIEGE · May 26, 2025

Keywords

ClinConnect Summary

The PARAGLIDE study is looking at two different techniques used to apply pressure on the throat during general anesthesia to see which one helps doctors get a better view of the vocal cords. This is important because a clear view can make it easier to insert a breathing tube safely. In this trial, patients will experience three different situations: no pressure at all, cricoid pressure (a common technique), and paratracheal pressure (another method). The study will help determine which method might work best for helping doctors manage airways during surgery.

To participate in this trial, you need to be at least 18 years old and scheduled for a surgery that requires general anesthesia and a breathing tube. You should be in generally good health with no previous issues with intubation or known problems with your airway. If you meet these criteria, you will be asked to give your written consent before taking part in the study. This is a great opportunity to contribute to research that could improve how anesthesia is managed in the future!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Scheduled for elective surgery under general anesthesia requiring endotracheal intubation
• • ASA physical status I or II
• • Normal airway anatomy as assessed by the anesthesiologist (Mallampati I-II, no known or anticipated difficult airway)
• • Written informed consent obtained prior to inclusion
• Exclusion Criteria:
• • History of difficult intubation or anticipated difficult airway
• • Known upper airway anatomical abnormalities (e.g., tumors, tracheal deviation, cervical spine instability)
• • BMI \> 35 kg/m²
• • Gastroesophageal reflux disease or increased aspiration risk
• • Pregnancy
• • Emergency surgery
• • Allergy or contraindication to any anesthetic drugs used
• • Inability to provide informed consent