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Search / Trial NCT07005167

Clinical Performance of Endocrowns Fabricated From Two Hybrid Ceramic Materials on Endodontically Treated Molars: A Randomized Clinical Trial

Launched by CAIRO UNIVERSITY · Jun 3, 2025

Trial Information

Current as of July 05, 2025

Not yet recruiting

Keywords

Hybrid Ceramics Cerasmart Hc Hard Blocks

ClinConnect Summary

This clinical trial is looking at the success of two different types of endocrowns, which are special dental restorations used to fix molars that have had root canal treatment. The main goal is to see how well these endocrowns stay in place over 6, 12, and 18 months. Researchers will also compare how often the restorations fail, how well they fit, their color and appearance, and how satisfied patients are with each type of crown.

To participate in this study, you need to be at least 21 years old, in good health, and willing to attend follow-up appointments for 18 months. You should have a molar that has had root canal treatment and enough remaining tooth structure to support the crown. However, certain conditions like severe gum disease or uncontrolled diabetes may prevent you from joining. If you are eligible, you’ll receive one of the two types of endocrowns, and your dental health will be monitored regularly throughout the study. This helps researchers understand which crown type works best for patients like you.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Age ≥21 years
  • 2. Good general health (ASA I or II)
  • 3. Willing and able to provide informed consent
  • 4. Committed to follow-up appointments for 18 months
  • 5. Root canal treated molars requiring restoration
  • 6. Adequate remaining tooth structure:
  • Minimum 2mm ferrule height
  • Sufficient wall thickness (≥1.5mm)
  • At least 2 remaining walls
  • 7. Opposing natural dentition or fixed prosthesis
  • 8. Adequate periodontal health:
  • Probing depth ≤4mm
  • No bleeding on probing
  • 9. Good oral hygiene with plaque score ≤20%
  • 10. Sufficient mouth opening for clinical procedures
  • 11. Normal occlusion and acceptable interocclusal space
  • Exclusion Criteria:
  • 1. Pregnant or lactating women
  • 2. Severe bruxism or parafunctional habits
  • 3. Active periodontal disease
  • 4. Active caries or inadequate oral hygiene
  • 5. Less than 2mm ferrule height after preparation
  • 6. Apical pathology or inadequate root canal treatment
  • 7. Tooth mobility grade II or III
  • 8. Known allergy to materials used
  • 9. Uncontrolled diabetes (HbA1c \>7.0%)
  • 10. Radiation therapy in head and neck region
  • 11. Temporomandibular joint disorders
  • 12. History of poor compliance with dental appointments
  • 13. Heavy smokers (\>10 cigarettes/day)
  • 14. Chronic use of medications affecting salivary flow
  • 15. Unable to understand study requirements
  • 16. Evidence of pulpal or periapical pathology

About Cairo University

Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.

Locations

Cairo, , Egypt

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported