THUMB: Multi-centre Cluster Trial for Caesarean Section Haemorrhage

Launched by BRUCE BICCARD · Jun 2, 2025

Keywords

ClinConnect Summary

The THUMB trial is a study aimed at improving care for women who need a cesarean section, especially to prevent excessive bleeding, known as postpartum hemorrhage. Researchers want to see if a special set of guidelines, called the 'Rule of THUMB,' can help healthcare providers better assess risks, diagnose problems, and follow proven methods to manage bleeding during and after surgery. They will also look at how different factors, like the hospital environment and teamwork, affect how well these guidelines work in real-life situations. The goal is to make improvements that can be used in hospitals across Africa in the future.

To participate in this trial, women who are scheduled to have a cesarean section at one of the participating hospitals can join. However, if a patient chooses not to be part of the study, they will be excluded. While the study is not yet recruiting participants, women who take part can expect to help improve healthcare practices that could benefit many others in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Any patient who requires a caesarean section in participating countries with hospitals that routinely perform caesarean section.
• Exclusion Criteria:
• • Patients who opt out of the trial will be excluded.