T2 Biomarkers Predictive Value in Occupational Asthma After Cessation of Exposure.

Launched by UNIVERSITY HOSPITAL, STRASBOURG, FRANCE · May 27, 2025

Keywords

ClinConnect Summary

This clinical trial is looking to understand how certain biological markers, called T2 biomarkers, can help predict whether patients with occupational asthma will experience improvement after they stop being exposed to harmful substances at work. Occupational asthma can develop when someone is exposed to certain triggers in their job, and while stopping the exposure can help, only about 30% of patients fully recover. Researchers want to see if measuring T2 biomarkers can help identify which patients are more likely to get better after they cease their exposure.

To participate in this study, you need to be over 18 years old and have been diagnosed with occupational asthma through a specific test. You should also have reduced or eliminated your exposure to the trigger causing your asthma. If you join the study, you will undergo a test to check how your lungs react and will have your T2 biomarkers measured. This research could lead to better ways of predicting recovery for people with occupational asthma in the future. The study is not yet recruiting participants, so keep an eye out for updates if you’re interested!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age over 18
• • Diagnosis of occupational asthma by specific inhalation challenge
• • Exposure to sensitizing agent avoided or reduced
• • Able to understand the aims and risks of the research and to give free and informed consent
• • For women of childbearing age: effective contraception in progress.
• • Benefiting from social security coverage
• Exclusion Criteria:
• • Impossibility of giving the subject informed information (subject in emergency situation, difficulties in understanding the subject)
• • Subject under court protection
• • Subject under guardianship or curatorship
• • Pregnant or breast-feeding patient