One-year Outcomes by Index Treatment in Elderly Patients With Acute Cholecystitis

Launched by INSTITUTO DE INVESTIGACIÓN SANITARIA Y BIOMÉDICA DE ALICANTE · Jun 4, 2025

Keywords

ClinConnect Summary

The GOLDENEYE study is a clinical trial aimed at understanding the best ways to treat elderly patients, aged 70 and older, who have acute cholecystitis, which is an inflammation of the gallbladder often caused by gallstones. The study is looking at different treatment options, including supportive care, draining the gallbladder through the skin, having surgery right away, or waiting to have surgery later. Researchers want to see how these treatments affect important outcomes for patients, such as their quality of life, how often they need further treatment, and their overall survival after one year.

To participate in this study, patients must be at least 70 years old and diagnosed with acute cholecystitis following specific guidelines. However, those with a history of certain other medical conditions, like previous gallbladder issues or serious illnesses, cannot join. Throughout the trial, participants will be monitored closely, and their data will be collected using a secure system to ensure accuracy. This research aims to provide valuable insights that could lead to better treatment options for older patients with this condition, ultimately improving their health and quality of life.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients ≥70 years
• • diagnosed with acute cholecystitis, as per the Tokyo guidelines
• Exclusion Criteria:
• • prior episodes of cholecystitis or pancreatitis
• • terminal illness
• • concurrent diagnosis of acute pancreatitis, cholangitis, bile duct disease, or digestive malignancy