A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population

Launched by DEVYSER INC. · May 28, 2025

Keywords

ClinConnect Summary

This clinical trial is focused on kidney transplant patients and aims to collect blood samples to help develop a new, non-invasive test. This test will look for a specific type of DNA found in the blood, called donor-derived cell-free DNA (dd-cfDNA). By detecting this DNA, researchers hope to better understand how well the transplanted kidney is functioning and whether it is healthy or facing problems.

To participate in this study, you must be at least 18 years old, have had a kidney transplant before joining the trial, and be scheduled for a specific kidney biopsy as determined by your doctor. You also need to be able to give your written consent to join the study. However, there are certain conditions that would exclude someone from participating, such as being pregnant or having received a blood transfusion in the last month. If you join the study, you can expect to provide blood samples that will be used for research, which could ultimately help improve care for kidney transplant patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Willing and able to provide written informed consent
• • 2. Is 18 years of age or older at enrollment
• • 3. Had a kidney transplant prior to enrollment
• • 4. Is having an indication biopsy as determined by clinician
• • 5. retrospective leftover samples are available from the recipient and the kidney donor(s).
• Exclusion Criteria:
• • 1. Is pregnant
• • 2. Had a blood transfusion within the past 4 weeks
• • 3. Had a transplant from an identical (monozygotic) twin
• • 4. Had transplants of multiple organs from the same donor (eg, kidney and liver transplant).
• • 5. Had transplants of more than 2 organs from different donors (eg, recipient of a third kidney transplant)
• • 6. Had a transplant of hematopoietic stem cells (eg, bone marrow) or tissue (eg, heart valve)