HerResolve™ in Detecting the Presence of Endometriosis Among Symptomatic Women

Launched by CHINESE UNIVERSITY OF HONG KONG · May 28, 2025

Keywords

ClinConnect Summary

The HerResolve™ clinical trial is studying a new way to detect endometriosis, a common condition that affects many women and can cause severe pelvic pain and difficulties with fertility. This trial is aimed at women aged 18 to 49 who have symptoms like pelvic pain or unusual bleeding and are scheduled for a type of surgery called laparoscopy. During this surgery, doctors will look for signs of endometriosis and take samples to confirm its presence or absence.

To participate, women must be able to provide consent and have their medical history reviewed. They should not have certain health issues, such as cancer, or be pregnant. Participants will have blood drawn at specific times during their menstrual cycle, and the study aims to gather important information to help improve how endometriosis is diagnosed. It's important to note that the trial is not yet recruiting participants, but it hopes to shed light on this challenging condition and offer better solutions for those affected.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Females aged 18 to 49 with mild to severe symptoms of pelvic pain and/or abnormal bleeding.
• • Diagnostic laparoscopy is scheduled with histology on any visually suspected endometriosis, and all reports (surgical and pathology) to confirm a positive result. If no visually suspicious endometriotic lesions are seen, biopsies from random areas during the laparoscopy procedure to confirm a negative histopathology result.
• • Blood drawn during secretory or proliferative phase of the menstrual cycle
• • Provide written informed consent to participate in the study and provide medical history on medications.
• Exclusion Criteria:
• • Patients who object to medical history collection and data requests
• • Patients with cancer and/or undergoing chemotherapy and/or radiotherapy
• • Patients who are unable or do not undergo laparoscopic surgery
• • Patients participating in additional interventional clinical studies
• • Pregnant, lactating, or subjects who are not healthy enough for blood donation.
• • Blood drawn during menses or ovulation phase of menstrual cycle
• • Females who are post-menopausa