Cardio-neural Pacing to Modulate AV Conduction in Persistent AF Patients - a Feasibility Study

Launched by CHINESE UNIVERSITY OF HONG KONG · May 28, 2025

Keywords

ClinConnect Summary

This clinical trial, titled "Cardio-neural Pacing to Modulate AV Conduction in Persistent AF Patients," aims to explore a new approach for managing persistent atrial fibrillation (AF), a common heart rhythm problem. The study is looking at a technique called cardio-neural pacing, which stimulates certain nerves around the heart to help control heart rate. This could potentially reduce the need for medications or procedures like pacemaker implantation in some patients. The researchers want to see if this method is safe and effective by gathering images and mapping the areas where pacing is applied.

To be eligible for this trial, participants need to be between 65 and 74 years old and have persistent atrial fibrillation that requires a pacemaker according to standard guidelines. Patients who are younger than 18, pregnant, unable to give informed consent, or illiterate cannot participate. If someone qualifies and decides to join, they can expect to have pacing applied in a way that is not painful, and researchers will monitor the effects on their heart rhythm. This trial is important as it may lead to better treatment options for patients with this condition in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with persistent atrial fibrillation who are scheduled for pacemaker implantation per guideline indication
• Exclusion Criteria:
• • Patients who cannot provide informed consent
• • Patients \< 18 years old
• • Pregnant patients
• • Illiterate patients