Smart Olfaction App to Reduce Relapse

Launched by UNIVERSITY OF HOUSTON · May 28, 2025

Keywords

ClinConnect Summary

This clinical trial is testing a new way to help people quit smoking by using a smartphone app that combines olfactory stimulation—using scents—to reduce cravings for cigarettes. The study will compare how effective this app, called Smart-T, is when combined with the olfactory stimulation system versus when it's used alone. Researchers hope that this innovative approach can make a real difference in helping people stop smoking.

To be eligible for the trial, you need to be at least 18 years old, smoke at least 5 cigarettes a day for over a year, and have a smartphone with internet access. You also need to be motivated to quit smoking and be willing to stop for either 14 days or 13 weeks, depending on which phase you participate in. If you join the study, you can expect to use the app regularly and participate in some assessments to track your progress. It’s important to note that people with certain health issues, like uncontrolled hypertension or recent heart attacks, won't be able to take part in this trial.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • At least 18 years of age
• • Ability to read, understand and speak English
• • Currently smoke at least 5 cigarettes daily for one year or longer
• • Do not currently smoke marijuana or currently smoke marijuana but willing to not smoke during the duration of the study
• • Have an active smartphone that is Apple or Android based
• • Have phone service including a data plan
• • Interested in downloading the study app onto their personal phone
• • Motivated to quit smoking
• • Willing and able to complete study procedures
• • Willing to quit smoking for 14 days (Phase I) or willing to quit smoking for 13 weeks (Phase II)
• Exclusion Criteria:
• • Olfactory dysfunction including inability to smell, a very weak or distorted sense of smell, or sensitivity to odors
• • Report any allergies or negative reactions to odors/fragranced products
• • Not being fluent in English
• • Being pregnant by self-report
• • Report hypertension that is not under control
• • Have had a heart attack within the past two weeks
• • Those who participated in Phase I will not be eligible to participate in Phase II
• • Have a smartphone that is not compatible with the Insight mHealth platform
• • Report using electronic cigarette or vaping device in the past 90 days