Risk Factors for Hospitalization and Transfusion Criteria in Patients With Dengue Virus Infection

Launched by JOSE IVAN RODRIGUEZ DE MOLINA SERRANO · Jun 3, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the factors that might lead to hospitalization and the need for blood transfusions in patients with dengue virus infection. Dengue is a viral illness that can cause fever and sometimes serious complications. The researchers want to learn more about the clinical signs and lab results that indicate when a patient may need to be hospitalized. They will also look at how often blood transfusions are used in these patients and how effective they are in helping recovery. This study will take place over three years at a hospital in northern Mexico, following patients from their first visit to the emergency department until they either recover or are discharged.

To be part of this study, participants need to be at least 5 years old and must have a confirmed dengue infection. They should be visiting the hospital for the first time regarding their dengue illness. The study is open to all genders, and participants—or their parents or guardians—will need to sign a consent form to take part. However, individuals with other infections, certain blood diseases, or who do not agree to participate will not be included. If eligible, patients can expect to have their health monitored closely during their treatment and recovery, contributing valuable information that could help improve care for future dengue patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged ≥5 years
• • Laboratory-confirmed dengue infection (NS1, IgM, or PCR)
• • First contact at emergency or outpatient services
• • Informed consent signed by the patient or legal guardian
• Exclusion Criteria:
• • Co-infection with other arboviruses or COVID-19
• • Pre-existing hematologic or oncologic disease
• • Refusal to sign informed consent