The Impact of OliPhenolia® Supplementation on Exercise Induced Inflammation and Functional Movement in Humans.

Launched by ANGLIA RUSKIN UNIVERSITY · May 29, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a product called OliPhenolia®, which is made from olives, on exercise-related inflammation and recovery in healthy adults. The researchers want to find out if taking OliPhenolia® can help reduce inflammation that occurs after exercise and improve how quickly people recover. They will do this by comparing OliPhenolia® to a placebo (a similar-looking product without the active ingredient) in two phases. In the first phase, participants will take a single dose of either OliPhenolia® or the placebo before a workout, and blood samples will be taken afterward to measure inflammation. In the second phase, participants will take OliPhenolia® or the placebo for 16 days, and then repeat the exercise and blood sampling to see if the longer use has a greater effect.

To participate in the trial, you need to be at least 21 years old and in good health, and you must be willing to follow the study's guidelines. Some people may not be eligible if they have certain health conditions, are on specific diets, or have recently engaged in heavy exercise. If you join the study, you can expect to take either the supplement or the placebo, participate in an exercise routine, and provide blood samples on several occasions to help the researchers understand how the product affects recovery from exercise.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 21 in line with manufacturer recommendations.
• • Written informed consent.
• • Willingness and ability to conform to the full protocol (please see full protocol).
• • Judged by the investigator to be in good health.
• • To have a pre-study health screen signed off by the lead researcher.
• Exclusion Criteria:
• • Current or recent (within the last 4 weeks) engagement with a strict dietary regime i.e., vegetarian / vegan / ketogenic / paleolithic / high protein / weight loss.
• • Any known issues with blood taking.
• • Any known bleeding disorders.
• • Any known allergy to olives, grapes, lemon, coca cola or prunes.
• • Average alcohol use of \<21 glasses per week for men and \<14 glasses per week for women (on average for the last six months).
• • Any drug or medicine abuse in the last six months
• • Known cardiovascular disease, disease related to the immune system (including HIV and hepatitis) and / or the respiratory system.
• • Known Diabetes Mellitus type I or type II.
• • Known renal or liver issues or known thyroid dysfunction.
• • Currently undertaking regular heavy and / or extreme exercise (please discuss with the lead researcher if you are unsure).
• • Current smoker or stopped smoking for \<one month prior to the first visit.
• • Current participation in any other clinical study within the month previous to the study start date (discuss with the lead researcher if unsure).
• • Known pregnancy and / or lactation (women only)
• • Uncertainty about the willingness or ability of the subject to comply with the protocol requirements.