Laparoscopic Pancreaticoduodenectomy

Launched by MINIA UNIVERSITY · Jun 5, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a type of surgery called laparoscopic pancreaticoduodenectomy (LPD), which is used to treat certain types of pancreatic and periampullary cancers. This surgery is considered less invasive than traditional methods, meaning it may lead to a quicker recovery and less pain for patients. The goal of the trial is to evaluate how safe and effective this surgical approach is for patients who are eligible and fit for the procedure.

To be eligible for this trial, participants should have specific types of pancreatic tumors that can be surgically removed, with no signs of cancer spread to other parts of the body. This includes patients with cancers of the pancreatic head, bile duct, duodenum, or ampulla. However, those who have serious health issues, inoperable tumors, or certain other medical conditions will not be able to participate. If you join this trial, you can expect to undergo the laparoscopic surgery and be monitored closely for your recovery, as researchers gather important information about the outcomes of this procedure.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Patients meeting the curative treatment intent in accordance with clinical guidelines:
• • No evidence of metastasis.
• • Radiological non-involvement of superior mesenteric vein \& portal vein.
• • Preserved fat planes between celiac axis, hepatic artery \& superior mesenteric artery.
• • Patients presenting with resectable pancreatic head cancer, cholangiocarcinoma, duodenal cancer and ampullary tumours who are fit for laparoscopic pancreaticoduodenectomy.
• Exclusion Criteria:
• • Unfit patients for surgery due to severe medical illness.
• • Inoperable patients with distant metastases, including peritoneal, liver, distant lymph node metastases, and involvement of other organs.
• • Irresectable tumors in diagnostic laparoscopy.
• • Patients requiring left, central or total pancreatectomy or other palliative surgery.
• • History of other malignant disease.
• • Pregnant or breast-feeding women.
• • Patients with serious mental disorders.
• • Patients with vascular invasion and requiring vascular resection as evaluated by the multidisciplinary team team according to abdominal imaging data.
• • Pancreatoduodenectomy for other diagnosis like cystic lesions, benign tumors or chronic calcific pancreatitis
• • Patients with cirrhotic liver.
• • Patients refused to participate in the study.