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Search / Trial NCT07010328

Integrating AI in Postural Rehabilitation for Parkinson's Disease

Launched by IRCCS NATIONAL NEUROLOGICAL INSTITUTE "C. MONDINO" FOUNDATION · May 29, 2025

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Physical Activity Neurological Disorder Artificial Intelligence

ClinConnect Summary

This clinical trial is studying the use of artificial intelligence (AI) to help improve posture in people with Parkinson's disease who have specific postural challenges, such as Pisa Syndrome or camptocormia. These conditions can cause significant difficulties, including leaning to one side or bending forward, which can lead to pain and balance issues. The researchers want to see if using an AI system that provides real-time feedback can help patients maintain better posture and improve their overall mobility and quality of life after they finish their initial rehabilitation in the hospital.

To be eligible for this study, participants need to be over 18 years old and have a diagnosis of Parkinson's disease. They should also be experiencing noticeable trunk postures, like bending forward or to the side. The study is currently looking for people who score above a certain level on a mental assessment test, ensuring they have the capacity to participate fully. If you join the trial, you'll be using a personalized exercise program at home, guided by AI, to help support your recovery and independence. This innovative approach aims to provide more effective and lasting benefits for those dealing with challenging postural issues related to Parkinson's disease.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age above 18 years
  • Diagnosis of Parkinson's disease according to MDS criteria
  • Hoehn and Yahr stage ≤ III
  • Clinical diagnosis of camptocormia (presence of an anterior axial trunk flexion of at least 30°), or of Pisa Syndrome (presence of a lateral trunk flexion of at least 10°) at the time of enrollment (T0)
  • Mini-Mental State Examination (MMSE) score \> 23
  • Exclusion Criteria:
  • Atypical parkinsonian syndromes
  • History of spinal surgery
  • Previous vertebral trauma
  • Current or past spinal tumors or infections
  • Idiopathic scoliosis
  • Ankylosing spondylitis
  • Spinal canal stenosis
  • Other neurological conditions
  • Severe dyskinesias

About Irccs National Neurological Institute "C. Mondino" Foundation

The IRCCS National Neurological Institute "C. Mondino" Foundation is a prominent research institution in Italy dedicated to advancing the field of neurology through innovative clinical trials and scientific research. As a recognized IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), the foundation focuses on the diagnosis, treatment, and rehabilitation of neurological disorders, fostering collaboration among healthcare professionals, researchers, and academic institutions. Committed to translating cutting-edge research into clinical practice, the foundation aims to enhance patient care and improve outcomes for individuals affected by neurological diseases. Its rigorous approach to clinical trials ensures the highest standards of scientific integrity and patient safety.

Locations

Pavullo Nel Frignano, Pavia, Italy

Patients applied

0 patients applied

Trial Officials

Luca Martinis

Principal Investigator

IRCCS Mondino Foundation

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported