The Effect of Physical Activity Levels on Dysmenorrhea Severity, Menstrual Symptoms, and Functional and Emotional Status in Women Diagnosed With Multiple Sclerosis

Launched by KARABUK UNIVERSITY · Jun 2, 2025

Keywords

ClinConnect Summary

Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune, and demyelinating disease that causes damage to the white matter of the central nervous system. It is typically seen between the ages of 20 and 40. The incidence of MS is reported to be three times higher in women than in men. Although its etiology is not definitively known, it is thought that a combination of genetic predisposition and a non-genetic trigger-such as a virus, metabolism, or environmental factors-leads to recurring immune attacks on the central nervous system, resulting in a self-sustaining autoimmune disorder.

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Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Female patients diagnosed with multiple sclerosis by a neurologist
• • Aged between 18 and 55 years
• • Having an active menstrual cycle
• • Having a regular menstrual cycle (24-35 days)
• • No physical or cognitive impairment that prevents participation in exercise
• • Willingness to participate in the study
• Exclusion Criteria:
• • Postmenopausal status
• • Pregnancy or breastfeeding
• • Use of hormonal contraceptives or intrauterine devices
• • Use of medication that may affect dysmenorrhea
• • History of any gynecological surgery
• • Presence of pelvic pathology, pelvic inflammatory disease, endometriosis, or other conditions causing secondary dysmenorrhea