Community Antibiotic Use, Susceptibility and ResisTance Among Patients With Urinary Tract Infections (CAST-UTI)

Launched by ST GEORGE'S, UNIVERSITY OF LONDON · Jun 4, 2025

Keywords

ClinConnect Summary

The CAST-UTI clinical trial is studying urinary tract infections (UTIs) to understand how bacteria causing these infections behave in patients who seek care at community drug retail outlets (like pharmacies) compared to those who go to hospitals. The main goal is to see how many bacteria are resistant to antibiotics in these different settings and to check if the treatment patients receive is appropriate. Researchers will also look at how the journey patients take to get treatment affects their use of antibiotics.

To participate in this study, you need to have symptoms of a UTI, such as painful urination, a strong urge to urinate, or discomfort in your lower abdomen. The study is open to people of all ages and genders, but those without UTI symptoms cannot join. If you decide to take part, you'll help researchers learn more about antibiotic resistance, which is an important issue for public health.

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• * Must have one or more of the following clinical presentations regardless of age:
• • acute (\< 2 weeks) dysuria. increased urinary urgency and frequency, irritation, discharge. increased lower abdominal pain or discomfort and sometimes gross haematuria.
• • In elderly patients with pre-existing urinary symptoms: increased acute urinary changes.
• Exclusion criteria:
• • People without symptoms of UTI.