Relationship Between Remimazolam and Etomidate in Induction of General Anesthesia

Launched by SECOND HOSPITAL OF SHANXI MEDICAL UNIVERSITY · Jun 8, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how two medications, remimazolam and etomidate, work together to help with the start of general anesthesia. Anesthesiologists often use these drugs together to make sure patients feel comfortable and safe during surgery. However, researchers want to find out the best way to combine these medications, including the right doses, so that patients can have the smoothest experience possible.

To participate in this trial, individuals must be between 18 and 60 years old and in good health, with a specific body mass index (BMI). However, people who have allergies to either medication, are pregnant or breastfeeding, have certain serious health conditions, or have used sedative drugs recently won't be eligible. Those who take part can expect to receive careful monitoring and support throughout the study to ensure their safety and comfort. Please note that the trial is not yet recruiting participants, so there will be more information available once it begins.

Gender

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Eligibility criteria

• Inclusion Criteria:
• • 1. Both sexes
• • 2. aged 18-60 yr
• • 3. ASA physical status I-II
• • 4. BIM: 18-28kg/m²
• Exclusion Criteria:
• • 1. allergic to remimazolam and etomidate
• • 2. in pregnancy or lactation
• • 3. serious cardiovascular diseases, long-term alcoholism
• • 4. used sedative drugs or opioids within 24 hours
• • 5. severe mental illness and myasthenia gravis -