Pre- and Post-Treatment Investigation of B12 and Folic Acid (Folate) Levels in Patients Receiving Antiepileptic (Anticonvulsant) Treatment for Neuropathic Pain

Launched by GAZIOSMANPASA RESEARCH AND EDUCATION HOSPITAL · Jun 5, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how levels of vitamin B12 and folic acid change in patients who are taking certain medications (called antiepileptics) for neuropathic pain, which is a type of pain caused by problems in the nervous system. The researchers want to understand if these medications might lead to deficiencies in these important vitamins, which can affect overall health. The trial is looking for participants aged 18 to 75 who have been diagnosed with neuropathic pain and whose vitamin levels have been tested, but who are not currently receiving vitamin B12 or folic acid treatments and do not have diabetes or severe liver or kidney issues.

If you choose to participate, you will provide information about your health and undergo tests to check your vitamin B12 and folic acid levels before and after starting antiepileptic treatment. This study is not yet recruiting participants, but it aims to gather valuable information that could help improve care for people with neuropathic pain in the future. If you have any questions or think you might be eligible, it's always best to talk to your healthcare provider.

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Eligibility criteria

• Inclusion Criteria:
• • Patients aged 18-75 years who have been diagnosed with neuropathic pain, whose vitamin B12 and folic acid levels have been analysed, who do not receive vitamin B12 and folic acid treatment, and who do not have diabetes mellitus, liver and kidney failure
• Exclusion Criteria:
• • Patients receiving vitamin B12 and folic acid therapy at the time of antiepileptic (anticonvulsant) drugs initiation, patients with hepatic and renal insufficiency