Probiotics' Effects on Hormones, Body and Mood in Obese Women

Launched by WECARE PROBIOTICS CO., LTD. · Jun 2, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how a special formula of probiotics, which are good bacteria that can help with digestion, affects hormone balance and fat metabolism in obese women. The goal is to see if these probiotics can help with weight management and improve mood by balancing hormones. The trial is currently recruiting participants who are female, aged 18 to 40, and have a body mass index (BMI) of 25 or higher, which means they are considered overweight. Participants will need to take the probiotics daily and provide samples of blood, urine, and stool during the study.

To join the trial, women must be willing to follow the study guidelines and have good hearing to understand the instructions. However, those with certain health conditions, such as severe digestive issues, neurological disorders, or a history of specific mental health disorders, may not be eligible. Participants can expect regular check-ins and support throughout the study, which will help researchers understand how probiotics might benefit their health and well-being.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age: 18 to 40 years old, female, BMI ≥ 25 kg/m2. Be willing to receive follow-up during the intervention period. Be willing to provide two blood, urine and fecal samples during the intervention period.
• • Be willing to take the compound probiotics by oneself every day during the intervention period.
• • Have good hearing and be able to hear and understand all instructions during the intervention period.
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• Exclusion Criteria:
• • Suffering from digestive system diseases, mainly gastrointestinal diseases (celiac disease, ulcerative colitis, Crohn's disease).
• • Suffering from severe neurological disorders (epilepsy, stroke, severe head trauma, meningitis within the past 10 years, brain surgery, brain tumor, long-term coma - excluding general anesthesia).
• • Have received/are currently receiving treatment for the following mental illnesses: alcohol/drug/substance abuse dependence, schizophrenia, psychosis, bipolar disorder.
• • Take medication for depression or low mood. Suffering from internal organ failure (such as heart, liver or kidney failure, etc.).
• • Have received radiotherapy or chemotherapy in the past. Have received general anesthesia surgery/procedures within the past three years, or plan to receive general anesthesia procedures/surgeries within the next three months during this trial.
• • Have suffered from hepatitis (hepatitis B, hepatitis C), HIV or syphilis in the past.
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