Comparative of Sequential Application of Pulsed Dye Laser and Potassium-titanyl-phosphate Laser Treatment for Capillary Malformations Versus Single Application

Launched by FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO RAMON Y CAJAL · Jun 3, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at different ways to treat port-wine stains, which are birthmarks caused by abnormal blood vessels in the skin. Researchers want to find out how effective and tolerable three types of laser treatments are: the pulsed dye laser (PDL), the potassium-titanyl-phosphate (KTP) laser, and a combination of both applied one after the other. Each participant in the study will receive all three treatments on different parts of their port-wine stain, and the main goal is to see how much the stains improve. They will also check how much pain participants feel during the treatments and how satisfied they are with the results.

To be eligible for this trial, participants must be at least 18 years old and have a port-wine stain. They should have certain skin types (Fitzpatrick skin types I-IV) and must not have any open wounds in the treatment area, be pregnant, have metal implants nearby, or have specific skin conditions that might cause problems with the treatment. The trial is currently recruiting participants of all genders, and those who join can expect to help researchers learn more about effective treatments for these types of skin marks.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18
• • Fitzpatrick skin types I-IV
• • Presence of port-wine stain
• Exclusion Criteria:
• • Open wounds in treatment area
• • Pregnancy
• • Nearby metal implants
• • Photodermatoses