The Characteristics of Oral Microbiota in Chronic Pancreatitis and Autoimmune Pancreatitis

Launched by RUIJIN HOSPITAL · Jun 4, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the bacteria found in the mouth, known as oral microbiota, in people with chronic pancreatitis and related conditions. Researchers believe that these bacteria might play a role in the development of pancreatic diseases, including pancreatic cancer. The goal of the study is to identify and compare the characteristics of oral microbiota in patients with chronic pancreatitis, pancreatic cancer, and autoimmune pancreatitis. By analyzing these bacteria, the researchers hope to gain insights that could improve understanding and treatment of these conditions.

To participate in the trial, individuals must be between the ages of 65 and 74 and be able to provide informed consent, meaning they understand the study and agree to take part. However, those who have had previous digestive system surgeries, are pregnant or breastfeeding, have certain infections or cancers, or have taken antibiotics or probiotics recently may not be eligible. Participants can expect to provide saliva samples, which will be analyzed for the types of bacteria present. This study is currently recruiting, and it aims to shed light on how oral bacteria may impact pancreatic health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • A dated and signed informed consent form cooperate to complete sample collection
• Exclusion Criteria:
• • Previous digestive system surgery; During pregnancy or lactation; Complicated with infectious diseases, malignant tumors or other digestive system diseases (such as inflammatory bowel disease, irritable bowel syndrome, abdominal diseases, gastroesophageal reflux, etc.); Antibiotics and immunosuppressive drugs were used within 30 days before sampling; Those who take probiotics daily.