A Study to Understand How the Study Medicine (PF-07976016) is Processed and Eliminated in Healthy Men

Launched by PFIZER · Jun 3, 2025

Keywords

ClinConnect Summary

This clinical trial is looking to understand how a study medicine called PF-07976016 is processed by healthy men. The research will help scientists learn how the body takes in and eliminates this medication. The study will last for about 12 weeks, and it's designed specifically for healthy male volunteers aged 18 to 65, who weigh more than 110 pounds and have a body mass index (BMI) between 17.5 and 32.

If you decide to participate, you'll undergo a series of tests and procedures to ensure your health and safety. However, some individuals may not be eligible to join. For example, if you have issues with bowel movements, certain medical conditions, or if you've used tobacco or drugs recently, you may not qualify. It's important to remember that this study is currently not recruiting participants yet, but if you're interested, you can keep an eye out for updates on when it begins.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Males, 18 to 65 years of age
• • BMI 17.5 to 32 kg/m2 and a total body weight \>50 kg (110 lb)
• • Willing and able to comply with all study procedures
• Exclusion Criteria:
• • History of irregular bowel movements or lactose intolerance
• • Any medical or psychiatric condition or laboratory abnormality or other condition that may increase the risk of study participation
• • Use of any prohibited or concomitant medication(s)
• • Presence of specified abnormalities on diagnostic assessments including clinical laboratory tests
• • Positive urine drug test
• • History of alcohol abuse or repeated binge drinking and/or any other illicit drug use or dependence
• • Use of tobacco/nicotine containing products in excess of the equivalent of 5 cigarettes/day
• • Previous administration of an investigational product within 30 days preceding the first dose of study medicine in this study.