Variability and Post-op AEs: Does Preoperative CardioPulmonary Variability Assessment Identify Risk of Postoperative Adverse Events Following Thoracic Surgery

Launched by OTTAWA HOSPITAL RESEARCH INSTITUTE · Jun 3, 2025

Keywords

ClinConnect Summary

This clinical trial is focused on improving the safety of major thoracic surgeries, like those for lung, esophageal, or gastric cancer. Researchers want to see if assessing how well a patient's heart and lungs respond to stress before surgery can help predict the risk of complications after the operation. By understanding this "cardiopulmonary variability," doctors hope to create more personalized care plans to prevent problems and improve recovery for patients undergoing these surgeries.

To participate in this study, you need to be an adult, at least 18 years old, and scheduled for a major thoracic surgery. However, if you have certain heart conditions like atrial fibrillation, are pregnant, or are undergoing emergency surgery, you won’t be eligible. If you join, you can expect to undergo a preoperative assessment that looks at your heart and lung function. This could help your healthcare team better understand your individual risk factors and tailor your care to ensure a safer surgical experience.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patient (≥18 years of age)
• • Patients undergoing major thoracic resection for lung, esophageal or gastric cancer or mediastinal tumour (at least lobectomy, pneumonectomy, esophagectomy, gastrectomy, or mediastinal tumour resection)
• Exclusion Criteria:
• • Urgent/emergent cases
• • Patients with pre-existing atrial fibrillation or arrhythmia (persistent/paroxysmal)
• • Patients that are pacemaker dependent
• • Patients unable to participate in preoperative testing protocol (CardioPulmonary Variability Assessment)
• • Patients that are pregnant