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Search / Trial NCT07018284

Postoperative Pain Evaluation After Obturation With Different Sealers

Launched by UNIVERSITY OF SIENA · Jun 4, 2025

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Bioceramic Sealers Resin Based Sealers Endodontics

ClinConnect Summary

This clinical trial is looking at the pain patients experience after having a root canal treatment, which is done on teeth with issues like pulpitis (inflammation of the tooth’s inner tissue) or pulp necrosis (death of that tissue). Researchers want to find out if the type of material used to seal the tooth after the procedure—either a bioceramic or a resin-based sealer—makes a difference in how much pain patients feel afterward. Participants will report their pain levels using a simple scale at three different times: right after the treatment, 24 hours later, and again after 72 hours.

To join the trial, you need to be at least 18 years old and have a tooth diagnosed with pulp necrosis or irreversible pulpitis. However, some people may not be eligible, such as those with certain health conditions that could affect healing or those whose teeth have specific problems like fractures. If you participate, you'll help researchers understand which sealing material might lead to less pain after root canal treatments, potentially improving comfort for future patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients aged 18 years and older. Teeth with a diagnosis of pulpal necrosis or irreversible pulpitis. Informed consent provided for data usage.
  • Exclusion Criteria:
  • Patients with systemic conditions that may impair healing (e.g., uncontrolled diabetes, immunosuppression).
  • Asymptomatic presentation
  • Teeth with root fractures, resorption, or open apices.
  • Incomplete clinical or radiographic records.
  • Cases with poor-quality radiographs or lack of standardization for evaluation

About University Of Siena

The University of Siena, a leading academic institution in Italy, is dedicated to advancing medical research and improving patient care through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university leverages its extensive expertise in various fields of healthcare to design and conduct rigorous studies that address critical medical questions. Committed to ethical standards and patient safety, the University of Siena aims to translate scientific findings into practical applications, ultimately enhancing treatment options and health outcomes for diverse populations.

Locations

Madrid, , Spain

Patients applied

0 patients applied

Trial Officials

José Aranguren, MsC

Study Director

Universidad Rey Juan Carlos , Madrid, Spain 28922

Simone Grandini, PhD

Principal Investigator

University of Siena

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported