Postoperative Pain Evaluation After Obturation With Different Sealers
Launched by UNIVERSITY OF SIENA · Jun 4, 2025
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at the pain patients experience after having a root canal treatment, which is done on teeth with issues like pulpitis (inflammation of the tooth’s inner tissue) or pulp necrosis (death of that tissue). Researchers want to find out if the type of material used to seal the tooth after the procedure—either a bioceramic or a resin-based sealer—makes a difference in how much pain patients feel afterward. Participants will report their pain levels using a simple scale at three different times: right after the treatment, 24 hours later, and again after 72 hours.
To join the trial, you need to be at least 18 years old and have a tooth diagnosed with pulp necrosis or irreversible pulpitis. However, some people may not be eligible, such as those with certain health conditions that could affect healing or those whose teeth have specific problems like fractures. If you participate, you'll help researchers understand which sealing material might lead to less pain after root canal treatments, potentially improving comfort for future patients.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients aged 18 years and older. Teeth with a diagnosis of pulpal necrosis or irreversible pulpitis. Informed consent provided for data usage.
- Exclusion Criteria:
- • Patients with systemic conditions that may impair healing (e.g., uncontrolled diabetes, immunosuppression).
- • Asymptomatic presentation
- • Teeth with root fractures, resorption, or open apices.
- • Incomplete clinical or radiographic records.
- • Cases with poor-quality radiographs or lack of standardization for evaluation
About University Of Siena
The University of Siena, a leading academic institution in Italy, is dedicated to advancing medical research and improving patient care through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university leverages its extensive expertise in various fields of healthcare to design and conduct rigorous studies that address critical medical questions. Committed to ethical standards and patient safety, the University of Siena aims to translate scientific findings into practical applications, ultimately enhancing treatment options and health outcomes for diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Madrid, , Spain
Patients applied
Trial Officials
José Aranguren, MsC
Study Director
Universidad Rey Juan Carlos , Madrid, Spain 28922
Simone Grandini, PhD
Principal Investigator
University of Siena
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported