Micro Assays for HemATology Malignancies Antibody Treatment

Launched by ASSISTANCE PUBLIQUE HOPITAUX DE MARSEILLE · Jun 4, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how the immune system can be used to help treat blood cancers, known as hematological malignancies. The researchers want to understand why some immune cells in patients don’t work effectively against cancer and how we can boost their ability to fight it. They will do this by testing the immune system's response and conducting genetic tests to identify factors that might be blocking its effectiveness. The goal is to eventually develop a simple test that doctors could use to improve treatment options for patients needing immunotherapy.

To be eligible for this trial, participants must be at least 18 years old and diagnosed with a hematological malignancy that could benefit from immunotherapy. They should be starting treatment or preparing for a transplant and must be able to understand the study information provided to them. The trial is not yet recruiting participants, but it aims to help those with blood cancers by finding out how to better activate their immune responses. If you or a loved one might be interested, it’s important to discuss it with the healthcare team to see if participating is a good option.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male or Female over 18 years of age
• • Patient with a hematological malignancy likely to benefit from immunotherapy (in any form; at the discretion of the referring physician)
• • Before the start of 1st-line treatment, successive lines or before autograft (chemotherapy-free for at least 4 weeks in these cases).
• • Patient has received information about the study and has not expressed opposition.
• • Patient who is a beneficiary or entitled beneficiary of a social security scheme
• Exclusion Criteria:
• • Person in a period of exclusion from another research protocol at the time the non-opposition is signed.
• * Subjects covered by articles L1121-5 to 1121-8 of the French Public Health Code, i.e. :
• • Persons deprived of their liberty by judicial or administrative decision
• • Persons subject to psychiatric monitoring under articles L3112-1 and L3113-1 who are not covered by the provisions of article L1121-8
• • Minors
• • Adults under legal protection or unable to express their consent.
• • A person who cannot read and understand the French language well enough to be able to consent to take part in research.