Ultrasound Assessment of Fetal Growth Parameters

Launched by THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY · Jun 11, 2025

Keywords

ClinConnect Summary

This is an observational study aiming to create reference ranges for normal fetal growth measurements in this population. Researchers will look at how measurements like the length of the clavicle (collarbone), the width and length of the scapula (shoulder blade), and the length of the sternum (breastbone) relate to how far along the pregnancy is and other growth markers. The goal is to understand whether these measurements can help predict perinatal outcomes for the baby and mother, without testing a treatment.

If you are eligible, you would be a pregnant, first-time and returning to pregnancy between 12 and 40 weeks with a singleton pregnancy and between 18 and 45 years old. About 1,000 participants may be enrolled by invitation at The First Affiliated Hospital of Xiamen University in Xiamen, China. Participation involves ultrasound measurements that are part of routine care, plus additional measurements for the study. This is non-drug research and is not expected to change your care; the study is currently enrolling, with results planned for a future completion around 2032. No study results are available yet.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Singleton pregnancy; The date of the last menstrual period was determined for each pregnant woman, and a history of regular menstrual cycles was confirmed; Pregnant women had no maternal diseases that could affect fetal growth and development, such as diabetes, pregnancy-induced hypertension, or chronic infections; Fetuses had no chromosomal or structural abnormalities; Gestational age (calculated based on the last menstrual period) was within 7 days of the ultrasound biometric measurements; Good image quality.
• Exclusion Criteria:
• • Multiple gestation, fetal demise, or stillbirth; Pregnancy complications or comorbidities affecting fetal growth; Clinically diagnosed fetal growth restriction (FGR); Confirmed pathogenic infections (serology-positive), including TORCH, HIV, RPR, or other infections; Prenatal ultrasound indicating fetal hydrops, structural anomalies, or chromosomal abnormalities; History of substance abuse (e.g., drugs, smoking, alcohol) or medication use in early pregnancy; Discrepancy between clinical gestational age and ultrasound-estimated gestational age; Lack of follow-up information.