Afterload Mismatch Predictive modLE for Transcatheter Edge-to-Edge Repair (AMPLE-TEER)
Launched by SUN YAT-SEN UNIVERSITY · Jun 5, 2025
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
The AMPLE-TEER trial is studying a new way to predict and manage a condition called afterload mismatch (AM) in patients with mitral insufficiency, which is when the heart's mitral valve doesn't close properly. This condition can lead to serious heart problems and is common in China. The trial focuses on adults who are undergoing a specific heart procedure called transcatheter mitral valve edge-to-edge repair (TEER). Researchers want to find out if patients develop AM after this procedure and identify factors that might increase the risk of AM. The goal is to create a tool that helps doctors make better decisions for their patients after surgery.
To be eligible for this trial, participants must be over 18 years old and scheduled for the TEER procedure during their hospital stay. They should also be able to give written consent to participate. If you or someone you know is considering this heart procedure, joining the AMPLE-TEER study could provide valuable insights into managing recovery and improving outcomes after surgery. Participants will be monitored closely, and their experiences will help shape future treatments for others with similar heart conditions.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients undergoing transcatheter mitral valve edge-to-edge repair (TEER) during hospitalization.
- • Aged over 18 yrs.
- Exclusion Criteria:
- • Patients unable to provide written consent.
About Sun Yat Sen University
Sun Yat-sen University, a prestigious institution located in Guangzhou, China, is dedicated to advancing medical research and healthcare innovations. As a leading clinical trial sponsor, the university leverages its extensive academic resources and collaboration with top-tier medical professionals to conduct rigorous clinical studies. Committed to improving patient outcomes and contributing to global health knowledge, Sun Yat-sen University focuses on a wide range of therapeutic areas, employing cutting-edge methodologies to ensure the integrity and efficacy of its research initiatives. Through its clinical trials, the university aims to foster scientific advancements and enhance the quality of care provided to patients both locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Guangzhou, Guangdong, China
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported