Assessment of Stroke Volume in Shock Using Echocardiography Versus Bioreactive Impedance

Launched by UNIVERSITY OF NEVADA, LAS VEGAS · Jun 5, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different methods to measure stroke volume, which is the amount of blood the heart pumps with each beat, in patients who are experiencing shock—a serious condition where the body doesn't get enough blood flow. The researchers want to see how closely the results from echocardiography (a test that uses sound waves to create images of the heart) match up with another non-invasive method called bioreactance. This study is important because accurate measurements can help doctors make better decisions about treating critically ill patients.

To participate in this trial, you need to be an adult aged 18 or older and have a clinical diagnosis of shock, such as low blood pressure that requires medication. You also need to be able to give consent or have someone legally authorized to give consent for you. However, if you are pregnant, have severe heart valve disease, or certain other health conditions, you would not be eligible. If you join the trial, you can expect to undergo both types of tests to measure your heart's function, which could help improve care for patients in similar situations in the future.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• • Age ≥ 18 years
• • Clinical diagnosis of shock as determined by the treating ICU physician (e.g., hypotension requiring vasopressors or evidence of end-organ hypoperfusion)
• • Able to obtain informed consent from the patient or a legally authorized representative
• • Enrollment within 24 hours of ICU admission
• Exclusion Criteria:
• • Pregnancy
• • Known severe aortic valve disease or dynamic left ventricular outflow tract obstruction
• • Morbid obesity (BMI \> 40) that precludes accurate echocardiographic imaging Presence of cardiac arrhythmias (e.g., atrial fibrillation with rapid ventricular response) affecting stroke volume measurements
• • Implanted cardiac assist devices (e.g., LVAD, pacemaker dependency)
• • Imminent death or decision for comfort care only