Muscle Vibration as a Countermeasure Against Hypoactivity-induced

Launched by CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE · Jun 12, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating a treatment called focal muscle vibration (FMV) to help prevent muscle weakness and loss that can happen when people are less active for a long time. When muscles aren't used, they can lose strength, and this study aims to see if FMV can help improve muscle function by stimulating the nerves that control the muscles. Researchers believe that using FMV might be an effective way to help people recover their strength and muscle mass.

To participate in this study, you need to be a healthy adult aged 18 to 45 with a normal body weight and at least 1.5 hours of exercise each week, like walking or cycling. The study is not yet recruiting, so participants can expect to engage in some sessions using the vibration device and provide feedback about their experience. There are certain health conditions and factors that might disqualify someone from joining, such as chronic illnesses or recent injuries, so it’s important to review the eligibility criteria carefully. Overall, this study could offer a new approach to help maintain muscle strength in those who may be at risk of weakness from inactivity.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Men and women.
• • Aged 18 to 45 years.
• • Body Mass Index (BMI) between 20 and 25 kg/m².
• • Engaging in at least 1.5 hours per week of physical activity (e.g., brisk walking, running, swimming, cycling).
• • Provided informed consent after receiving detailed information about the study.
• • Affiliated with or beneficiaries of a social security system
• Exclusion Criteria:
• • Chronic cardiovascular, neuromuscular, bone, metabolic, and/or inflammatory disorders.
• • Personal history and/or risk factors for thrombosis.
• • Use of antidepressant medications.
• • Use of neuroactive substances likely to alter corticospinal excitability (e.g., hypnotics, antiepileptics, psychotropics, muscle relaxants) during the study.
• • Recent bone or ligament trauma within the past 12 months.
• • Inability to perform the physical efforts required for the study.
• • Recent participation in a sporting competition or intense, unusual physical activity within the past month.
• • Corticosteroid treatment within the past 3 months.
• • Any skin lesions at the planned vibrator application site.
• • Simultaneous participation in another interventional medical study.
• • Pregnant or breastfeeding women.
• • Individuals unable to understand the purpose and conditions of the study or unable to provide informed consent.
• • Individuals deprived of liberty or under guardianship