Sepsis and Hospital Mortality

Launched by UNIVERSITY OF CALABRIA · Jun 6, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at sepsis, a serious condition that can lead to death in hospitals, especially among patients receiving intensive care. The goal of the study is to find better ways to diagnose sepsis more quickly and accurately. Researchers will be examining changes in blood plasma using special equipment to see if these changes can help identify severe infections earlier than current methods.

To participate, you need to be at least 18 years old and fall into one of several groups: you could be a cardiology patient without an infection, someone with sepsis, or a patient with a hospital-acquired infection. However, if you have certain health conditions, like severe autoimmune diseases or are on specific medications, you may not be eligible. If you decide to take part, you'll be asked to provide written consent, and the process will involve non-invasive tests to gather important data. This research aims to improve outcomes for patients with sepsis, making early detection easier and potentially saving lives.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Cardiology patients without documented infection (Control Group)
• • Patients with sepsis
• • Patients with nosocomial infection
• • Patients with myocarditis, endocarditis, or pericarditis
• • Ability to provide written informed consent
• Exclusion Criteria:
• • Patients with severe or chronic medical conditions that may interfere with study results, such as autoimmune diseases, renal or hepatic failure
• • Patients taking medications that could affect the measured biophysical parameters, such as corticosteroids or immunosuppressants
• • Patients with cancer
• • Patients with diseases involving the immune system (e.g., lymphomas, leukemias)
• • Patients with congenital or acquired immunodeficiencies (e.g., HIV)
• • Patients who are unable to read and sign the informed consent form