Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals

Launched by AIN SHAMS UNIVERSITY · Jun 7, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating how caffeine, specifically from green tea, can help reduce the severity of acute migraine attacks. Researchers want to see if taking caffeine can make migraine pain less intense for patients who experience different types of migraines, including those with and without aura (visual or sensory disturbances that can happen before a headache). The study is currently looking for participants aged between 18 and 65 who have been diagnosed with migraines according to specific medical guidelines.

To be eligible for the study, participants must have a history of migraines but should not have certain health issues like heart problems, active ulcers, or severe mental health conditions that could affect their ability to participate. If you join the trial, you can expect to receive caffeine and report how it affects your migraine pain using a simple scoring system. This study aims to find out if caffeine can be an effective treatment option for managing acute migraines.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients suffering from migraine with aura, migraine without aura, episodic, and chronic migraine according to ICHD-3 diagnosis will be legible for the study.
• Exclusion Criteria:
• • Patients who have history of any cardiac dysrhythmia, hypertension, ischemic heart disease, active peptic ulcer disease, inflammatory bowel disease, obsessive compulsive disorder, pregnancy, breast-feeding, renal failure, hepatic failure, sleep disorder, mental retardation, and history of substance abuse that prevent them from cooperating with us during the study Patients who had headache due to: Cluster headache, trigeminal neuralgia, glossopharyngeal neuralgia, headache secondary to trauma, cranial disorder, vascular disorder, infection, or mass lesion, will also be excluded