The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
Launched by MASSACHUSETTS GENERAL HOSPITAL · Jun 6, 2025
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
The Million Anesthesia Cases Study (MACS) is a research study looking at how the rules about fasting before surgery might affect patients' health and comfort. Traditionally, patients are asked to stop eating and drinking for a certain period before undergoing anesthesia or surgery. However, early findings suggest that this fasting could have negative effects, such as increasing anxiety, thirst, and even causing issues like low blood pressure or problems with blood sugar levels. The study aims to understand these potential risks better and hopes to improve fasting guidelines for the millions of patients who face these procedures every year.
To participate in this study, you need to be undergoing a diagnostic or therapeutic procedure that involves anesthesia, whether it's general anesthesia, sedation, or a mix of both. Unfortunately, if you are not receiving anesthesia or if your medical records are not available in the Epic system, you won't be able to take part. As a participant, you can expect to share your experiences and health information, which will help researchers gather important insights about preoperative fasting and its effects on patients. Your involvement could help shape future practices that benefit countless patients like you.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Diagnostic or therapeutic procedure with anesthesia care (general anesthesia, regional anesthesia, sedation, or a combination of the above)
- Exclusion Criteria:
- • Not receiving anesthesia care
- • Lack of medical record data in Epic electronic medical record system
About Massachusetts General Hospital
Massachusetts General Hospital (MGH) is a leading academic medical center located in Boston, Massachusetts, renowned for its commitment to advancing medical research and patient care. As a prominent teaching hospital affiliated with Harvard Medical School, MGH plays a pivotal role in clinical trials across a wide range of disciplines, including cardiology, oncology, neurology, and more. The institution is dedicated to fostering innovative research that translates into effective therapies and improved health outcomes. MGH's Clinical Trials Office provides comprehensive support to facilitate the design, implementation, and management of clinical studies, ensuring adherence to the highest ethical standards and regulatory compliance. With a focus on collaboration and patient-centered care, MGH strives to enhance medical knowledge and contribute to the future of healthcare.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Boston, Massachusetts, United States
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported