Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

Launched by ALLEGHENY SINGER RESEARCH INSTITUTE (ALSO KNOWN AS ALLEGHENY HEALTH NETWORK RESEARCH INSTITUTE) · Jun 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how different exercise programs affect women who have finished treatment for breast cancer. Specifically, it looks at four types of group exercise routines focused on strength training to see how they improve fitness, muscle growth, and body fat. The goal is to find out which exercise plans help women build muscle and improve their overall conditioning after breast cancer treatment.

Women between 20 and 89 years old who have been treated for breast cancer (including surgery, radiation, chemotherapy, or hormone therapy) and who have some experience with guided strength training may be eligible to join. Participants will take part in monitored group exercise sessions and have their fitness, muscle size, and fat measured over time. Women currently receiving chemotherapy or those with certain health issues, like severe joint problems or on specific medications, cannot join. This study is still recruiting, and it offers an opportunity for breast cancer survivors to safely improve their strength and fitness after treatment.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 20-89 years
• • 2. Women prescribed exercise as a Standard of Care
• • 3. Women with a biopsy proven diagnosis of ductal carcinoma in situ (DCIS) or invasive carcinoma of the breast
• • 4. Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy.
• • 5. Women undergoing active chemotherapy are not allowed on study. Immunotherapy or targeted agent usage is allowed.
• • 6. Women with \> 6 months of resistance training experience under expert guidance by a CSCS
• Exclusion Criteria:
• • 1. Any current treatment with cytotoxic chemotherapy for breast cancer
• • 2. Inability to safely engage in group sessions of resistance training as deemed by study Pl
• • 3. Severe arthritic, joint, cardiovascular, or musculoskeletal condition deemed by Pl to be unsafe to engage in resistance training
• • 4. Beta blocker or GLP-1 inhibitor medications
• • 5. Pregnant women
• • 6. Males