Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal Sinus

Launched by SEHIT PROF. DR. ILHAN VARANK SANCAKTEPE TRAINING AND RESEARCH HOSPITAL · Jun 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to treat pilonidal sinus disease, a common condition that causes painful sores near the tailbone, mostly affecting young adults. The study compares two treatments: laser therapy alone versus laser therapy combined with a special chemical called phenol. Both treatments are done in a simple outpatient procedure using local anesthesia, meaning you won’t be put to sleep. The goal is to see if adding phenol helps wounds heal faster, reduces pain, and allows people to get back to their daily activities more quickly.

Adults aged 18 and older with a straightforward case of pilonidal sinus (meaning three or fewer small openings or “pits”) may be eligible to join. People with more complicated conditions, ongoing infections, or who have had previous pilonidal surgery are not eligible. If you join, you will be randomly assigned to one of the two treatment groups and followed for three months to track healing, pain, and quality of life. This study hopes to find better ways to treat pilonidal sinus disease, helping patients recover faster and feel more comfortable.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 18 years and older
• • Primary pilonidal sinus disease
• • Three or fewer pit counts
• • Willing to participate in the study and signed informed consent form
• • Able to attend follow-up visits
• Exclusion Criteria:
• • Age under 18 years
• • More than three pit counts
• • Acute abscess presentation
• • Bilateral lateral extension
• • Recurrent pilonidal sinus disease
• • Immunocompromised patients
• • Patients unable to attend follow-up visits
• • Pregnancy (if applicable)
• • Severe comorbidities that contraindicate surgery under local anesthesia