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Search / Trial NCT07024433

Tubeless Anesthesia in Preventing Lung Complications in Patients Undergoing Surgery for Early-Stage Lung Cancer

Launched by FUJIAN MEDICAL UNIVERSITY UNION HOSPITAL · Jun 9, 2025

Trial Information

Current as of July 09, 2025

Recruiting

Keywords

Early Stage Lung Cancer Tubeless Anesthesia Single Port Thoracoscopic Surgery

ClinConnect Summary

This clinical trial is studying a new way to give anesthesia called "tubeless anesthesia" during a type of minimally invasive lung surgery for patients with early-stage lung cancer. Unlike traditional anesthesia, which uses a breathing tube, tubeless anesthesia allows patients to breathe on their own during surgery. Researchers want to see if this method can reduce lung problems after surgery, improve how stable patients’ vital signs are during the operation, lower complication rates, and help patients recover faster.

People who may be eligible for this study are adults aged 18 to 70 with good heart and lung health who are scheduled for single-port thoracoscopic surgery to remove one or more lung nodules. Participants should be able to follow the study plan and agree to take part voluntarily. Patients who are very overweight, have certain lung diseases, or other health issues that make breathing or surgery riskier may not qualify. If you join the study, you can expect careful monitoring during and after surgery to compare the new anesthesia method with the traditional one, with the goal of improving safety and recovery for lung cancer surgery patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Age ≥18 years and ≤70 years;
  • 2. ECOG performance status score 0-1;
  • 3. Good cardiac and pulmonary function;
  • 4. Single or multiple peripheral lung nodules planned for single-port thoracoscopic surgery, with or without mediastinal lymph node dissection or sampling;
  • 5. Able to comply with the study visit schedule and other protocol requirements;
  • 6. Signed informed consent and voluntary participation in the study.
  • Exclusion Criteria:
  • 1. Obese patients (BMI \>30);
  • 2. Patients with difficult intubation or expected complex airway management;
  • 3. COPD patients with copious airway secretions;
  • 4. Patients with neurological dysfunction or who cannot cooperate while awake;
  • 5. Patients expected to have extensive pleural adhesions or with previous lung resection;
  • 6. Elderly and frail patients with severe hypoxia (PaO2 \<60 mmHg) or hypercapnia (PaCO2 \>50/55 mmHg);
  • 7. Previous induction chemotherapy or chemoradiotherapy;
  • 8. Intraoperative need to isolate the lung to prevent spillage and contamination of the contralateral lung;
  • 9. Patients expected to have large surgical wounds and lengthy procedures, clinically assessed as unsuitable;
  • 10. Patients whose cardiac and pulmonary function, or overall health, cannot withstand the procedure.

About Fujian Medical University Union Hospital

Fujian Medical University Union Hospital is a leading medical institution in China, dedicated to advancing healthcare through innovative clinical research and comprehensive patient care. As a prominent clinical trial sponsor, the hospital is committed to conducting high-quality studies that contribute to the development of new therapies and medical interventions. With a multidisciplinary team of experienced healthcare professionals and researchers, Fujian Medical University Union Hospital emphasizes ethical standards, patient safety, and scientific rigor in all its clinical trials, fostering collaboration with both local and international research partners to enhance medical knowledge and improve patient outcomes.

Locations

Fuzhou, Fujian, China

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported