Comparison of Cardiovascular Risks Between Hip Fracture Surgery With Continued DAPT（Dual Antiplatelet Therapy ） Within 6 Weeks vs After 6 Weeks Post-PCI（Percutaneous Coronary Intervention）: A Prospective Observational Cohort Study

Launched by FUJIAN MEDICAL UNIVERSITY UNION HOSPITAL · Jun 9, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether it is safe to perform hip fracture surgery within six weeks after a heart procedure called PCI (Percutaneous Coronary Intervention) without stopping a common blood-thinning treatment known as dual antiplatelet therapy (DAPT). Normally, patients who have had PCI are advised to wait several weeks before having surgery to reduce the risk of heart complications or bleeding. However, delaying hip fracture surgery can lead to serious problems like poor healing, bedsores, or infections. This study aims to see if early surgery while continuing blood thinners can be done safely, which could help patients recover faster and improve their quality of life.

People who might be eligible for this study are adults who have recently had PCI, are currently taking DAPT, have a body weight within a certain healthy range, and have no major heart or other organ problems before surgery. Participants will undergo hip fracture surgery without stopping their blood-thinning medication, and doctors will closely watch for heart and bleeding complications after surgery. The goal is to find a safer way to treat hip fractures soon after PCI, reducing risks and helping patients get back on their feet sooner.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Normal hs-cTnI levels prior to NCS BMI 20-28 kg/m² Post-PCI procedure, currently on regular DAPT therapy Complete PCI procedural documentation (date, quantity, stent type) Mentally sound, capable of normal communication
• Exclusion Criteria:
• • Abnormal hs-cTnI before NCS; Accompanied by dysfunction of other organs History of other major surgeries Risk factors for stent thrombosis (age \>79 years, impaired left ventricular function, stent implantation due to acute coronary syndrome, multiple stents, diabetes, renal insufficiency with creatinine \>1.5 mg/dl) Abnormal coagulation function Local anesthesia surgery Inability to cooperate