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Search / Trial NCT07025122

Fatigue in Multiple Sclerosis and Its Relationship to Inflammatory and Neurodegenerative Markers of the Disease

Launched by UNIVERSITY HOSPITAL, MARTIN · Jun 9, 2025

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Fatigue, Mitochondriopathy, Neurofilaments, Gfap, Genetics Intergenic Variant Near Bcl6 Intronic Variant In Os9

ClinConnect Summary

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the CNS, leading to non-traumatic neurological impairment in young people. Disability progression in MS is commonly recognized as the disability worsening occurring in patients with progressive MS or in the absence of relapse activity in relapsing progressing MS. This process can begin early in the disease and is not always halted by current therapeutics. The ability to accurately select between active, active progressive and nonactive progressive patients is crucial.

The aim of the proposed study is to use ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Clinical diagnosis of multiple sclerosis using McDonald2017 criteria Patients indicated to immunomodulatory treatment
  • Exclusion Criteria:
  • Multimorbidities

About University Hospital, Martin

University Hospital Martin is a leading academic medical center dedicated to advancing healthcare through innovative research and clinical trials. With a commitment to patient-centered care and cutting-edge medical practices, the hospital collaborates with a diverse array of researchers and healthcare professionals to explore new therapeutic approaches and improve patient outcomes. Its state-of-the-art facilities and multidisciplinary teams enable the rigorous evaluation of novel treatments, contributing to the global body of medical knowledge while enhancing the quality of care provided to the community.

Locations

Martin, , Slovakia

Patients applied

0 patients applied

Trial Officials

Petra Hnilicová, PhD Ing

Study Chair

Comenius University

Ema Kantorová, prof MD PhD

Principal Investigator

UHMartin and Comenius University

Martin Kolísek, assoc.prof RNDr, Dr.rer.nat.

Study Chair

Comenius University

Štefan Sivák, prof.MD, PhD

Study Director

UHMartin and Comenius University

Natália Huňarová, Mgr, doctorand

Study Chair

Comenius University

Andrea Ižarik Verešpejová, Mgr, doctorand

Study Chair

Comenius University

Daniel Čierny, associate prof, MD, PhD

Study Chair

UHMartin and Comenius University

Vladimír Nosáľ, associate prof, MD, PhD

Study Chair

UHMartin, Comenius University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported