Does Intralipid Infusion Can Reverse the Spinal Anesthesia Effect in Day Case Surgery?

Launched by BENHA UNIVERSITY · Jun 10, 2025

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ClinConnect Summary

This clinical trial is studying whether giving a medicine called intralipid can help reverse the effects of spinal anesthesia used during short, same-day surgeries. Spinal anesthesia is a type of pain relief injected near the spine to numb the lower part of the body during surgery. The researchers want to see if intralipid infusion can speed up recovery from this numbness, helping patients feel normal sooner after their procedure.

The study is looking for adults aged 18 to 65 who are healthy enough for outpatient surgery and scheduled for a planned surgery lasting less than 90 minutes under spinal anesthesia. Both men and women can join, but people with allergies to local anesthetics, those on blood thinners, pregnant women, emergency cases, or those not suitable for outpatient surgery won’t be eligible. Participants can expect to receive spinal anesthesia as usual and then be given intralipid to see if it helps reverse the numbness faster. This study is not yet recruiting, but it aims to improve recovery times for patients having quick surgeries.

Gender

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Eligibility criteria

• Inclusion Criteria:
• • Age from 18 to 65 years.
• • Both sexes.
• • American Society of Anesthesiology (ASA) physical status I-II.
• • Scheduled for day-case surgery under spinal anesthesia.
• • Time of surgery less than 90 min.
• Exclusion Criteria:
• • Patients with contraindications for outpatient surgery or spinal anesthesia.
• • Local anaesthetic (LA) allergy.
• • Those receiving anticoagulant therapy.
• • Emergency cases.
• • Pregnant cases.