Radicle Energy™: A Study Assessing the Impact of Health and Wellness Products on Fatigue

Launched by RADICLE SCIENCE · Jun 10, 2025

Keywords

ClinConnect Summary

This clinical trial, called Radicle Energy™, is looking at how certain health and wellness products might help reduce feelings of fatigue, or extreme tiredness. The study is designed to compare these products to a placebo (a harmless, inactive substance) to see if they really make a difference in how people feel. The research is done in a way that neither the participants nor the researchers know who is taking the real product or the placebo until the study ends, which helps keep the results fair and accurate.

To join, you need to be an adult living in the United States, at least 21 years old, and open to trying the study product without knowing exactly what it is until the study finishes. The study is open to all genders and backgrounds. However, some people cannot participate, such as those who are pregnant, breastfeeding, have certain serious health issues, or are taking specific medications that might interact with the study products. Participants will need to have internet access and be willing to share some health information over time. If you join, you can expect to use the study product or placebo and report on how your fatigue and related health feelings change during the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults, at least 21 years of age at the time of electronic consent, inclusive of all ethnicities, races, and gender identities
• • Assigned sex at birth will determine sex-specific recruitment and surveys (male vs female) employed, when needed
• • Resides in the United States
• • Has the opportunity for at least 30% improvement in their primary health outcome
• • Expresses a willingness to take a study product and not know the product identity (active or placebo) until the end of the study
• Exclusion Criteria:
• • Report being pregnant, trying to become pregnant, or breastfeeding
• • Unable to provide a valid US shipping address and mobile phone number
• • Reports current enrollment in another clinical trial
• • Reports being a heavy drinker (defined as drinking 3 or more alcoholic beverages per day)
• • Unable to read and understand English
• • Reports a current and/or recent (up to 3 months ago) major illness and/or surgery that poses a known, significant safety risk.
• • Reports a diagnosis of cardiac dysfunction, liver or kidney disease that presents a known contraindication and/or a significant safety risk with any of the study product ingredients.
• • NYHA Class III or IV congestive heart failure, atrial fibrillation, uncontrolled arrhythmias, cirrhosis, end-stage liver disease, stage 3b or 4 chronic kidney disease, or kidney failure
• • Reports taking medications that have a well-established moderate or severe interaction, posing a substantial safety risk with any of the study product ingredients.
• • Anticoagulants, antihypertensives, anxiolytics, antidepressants, chemotherapy, immunotherapy, sedative hypnotics, seizure medications, medications that warn against grapefruit consumption, corticosteroids at doses greater than 5 mg per day, diabetic medications, oral anti-infectives (antibiotics, antifungals, antivirals) to treat an acute infection, antipsychotics, MAOIs, or thyroid products
• • Reports current use of the primary ingredient(s) and/or similar product(s) to the active study product(s) that may limit the effects of the study products and/or pose a safety risk
• • Lack of reliable daily access to the internet